Tags Posts tagged with "pharmacology"


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What is pharmacology?

The word of pharmacology has gone through years of evolution. At the beginning, the means of pharmacology was the obvious response of the biological drugs explained by the scientists. Nowadays, pharmacology starts to explore the molecular function caused by the biological chemicals. That is the narrow sense of the word. For the broad interpretation, pharmacology is telling us how the natural chemical drug and the synthetic chemical drug make influence on the biological mechanism of the creatures, including the exploration of the derivation, chemical ingredients, psychological and physiological reactions, behavior mechanisms, and the drug uses in therapeutic and non-therapeutic fields. Pharmacology can also reflect the usage of many activities in subcellular, systemic, physiological or the behavior aspects of chemical drugs. It stops diseases and helps to treat them as well. On reducing the further damage of the pesticides and herbicides, it solves greatly.

What is pharmacology?

As the bridge science between the knowledge and the skills, pharmacology get all the subjects together, like molecular biology, cell biology, biochemistry, physiology and so on. Because of those multisubjects, pharmacology has the ability to translate all the knowledge into the reasonable direction of the treatment. As a result of the mutidisciplines, pharmacology has a distinct opinion towards the difficulties in drug-, medical- or the hormone- fields.

With the principles of the pharmacology, pharmacologists get a great number of chances to answer and solve questions or problems which can not be dealt with by other sciences. Pharmacology can be potential and be applicable in the research and application, which welcome more and more scientists to learn pharmacology and become pharmacologists.

When to explore pharmacology

In general, pharmacology is the science including the knowledge and skills, it shows the drug action of the chemical mechanisms on biology systems. If you are interested in understanding the disease development completely in both the previous or current studies, if you have great motivation and confidence to seek medical drug sciences, if you get the idea to find new and creative therapies in the development of medicals, you are suitable to explore pharmacology.

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A drug used in the treatment of leukemia can improve the cognition, physical activity and non action function in patients with Parkinson’s disease and Lewy. In addition, the drug may also cause significant changes in the toxic proteins associated with disease progression. The researchers introduced the results on the pharmacology conference.

The drug’s name is nilotinib. In 6 months study, the researchers conducted a dose escalation study of 12 patients. The results showed that the drug could benefit all patients who completed the study, including 10 patients who reported that they had a meaningful clinical improvement. Some good changes were also shown in the cerebrospinal fluid of the patients with Parkinson’s disease. The researchers explained that the changes in Tau, p-Tau, a-synuclein and Abeta-40 in the cerebrospinal fluid of the patient showed a clear change in the brain of the patient.

However, the study did not set up a reasonable control study group. People should be cautious in interpreting the results of this study.pharmacology

The researchers noted that the study’s main goal is to test the safety of drug use. The drug concentrations used in the study were much lower than the drug concentrations used in cancer treatment, and the patient did not show a serious side effect.

The use of this is very significant drug for the treatment of many patients, including the body’s ability to act and non action improvement. The researchers reported that one of the patients in a wheelchair could even walk again, while the other three patients who lose their ability to speak also could talk with others.

The researchers also explained the possible mechanism, “when using high dose drug for the treatment of CML, the drug can force the cancer cells to have autophagy, and promote cancer cell to death. In this study, a small dose of drug treatment will also open 4 to 8 hours autophagy a day, helping cells to remove toxic proteins without causing cell death. ”
This study is a new hope for patients with Parkinson’s disease and other neurodegenerative diseases.